PUBLICATIONS

  1. Scott JD and Fothergill JE (1982) A general method for affinity purification of complement component C3b using factor H-sepharose. Biochemical Journal 205:575-580.
  2. Scott JD, Dunbar B, and Fothergill JE (1983) The structural characterization of fragments produced by inactivation of the third component of complement by Factor I. Immunobiology 164:240-241.
  3. Scott JD, Fischer EH, Demaille JG, and Krebs EG (1985) Identification of an inhibitory region of the heat-stable protein inhibitor of the cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences USA 82:4379-4383.
  4. Scott JD, Fischer EH, Takio K, Demaille JG, and Krebs EG (1985) Amino acid sequence of the heat-stable inhibitor of the cAMP-dependent protein kinase from rabbit skeletal muscle. Proceedings of the National Academy of Sciences USA 82:5732-5736.
  5. Ballou LA, Villa-Moruzzi E, McNall SJ, Scott JD, Blumenthal DK, Krebs EG, and Fischer EH (1985) Structure, properties and regulation of phosphorylase phosphatase. Advances in Protein Phosphatases 1:21-27.
  6. Scott JD, Glaccum MA, Fischer EH, and Krebs EG (1986) Primary-structure requirements for inhibition by the heat-stable inhibitor of the cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences USA 83:1613-1616.
  7. Malencik D, Scott JD, Fischer EH, Krebs EG, and Anderson SA (1986) Association of calmodulin with peptide analogues of the inhibitory region of the heat-stable protein inhibitor of adenosine cyclic 3′,5′-phosphate dependent protein kinase. Biochemistry 25:3502-3508.
  8. Toda T, Cameron S, Sass P, Zoller M, Scott JD, McMullen B, Hurwitz MD, Krebs EG, and Wigler M (1987) Cloning and characterization of BCY1 a locus encoding the regulatory subunit of the cAMP-dependent protein kinase in Saccharomyces cerevisiae. Journal for Molecular and Cellular Biology 7:1371-1377.
  9. Scott JD, Glaccum MB, Zoller M, Uhler MD, Helfman DM, McKnight GS, and Krebs EG (1987) The molecular cloning of a type II regulatory subunit of the cAMP-dependent protein kinase from rat skeletal muscle and mouse brain. Proceedings of the National Academy of Sciences USA 84:5192-5196.
  10. Kennelly PJ, Takio K, Blumenthal DK, Edelman AM, Glaccum MB, Klevit RE, Roush CL, Scott JD, Titani K, Walsh KA, and Krebs EG (1987) Organization of myosin light chain kinase from rabbit skeletal muscle. Proceedings of the 5th International Symposium on Calcium Binding Proteins. Calcium-Binding Proteins in Health and Disease 494-504.
  11. Roush CL, Kennelly PJ, Glaccum MB, Helfman DM, Scott JD, and Krebs EG (1988) Isolation of the cDNA encoding rat skeletal muscle myosin light chain kinase: sequence and tissue distribution. Journal of Biological Chemistry 263:10510-10516.
  12. Oyen O, Scott JD, Cadd GG, McKnight GS, Krebs EG, Hansson V, and Jahnsen T (1988) A unique mRNA species for a regulatory subunit of cAMP-dependent protein kinase is specifically induced in haploid germ cells. FEBS Letters 229:391-394.
  13. Oyen O, Myklebust F, Scott JD, Hansson V, and Jahnsen T (1989) Human testis cDNA for the regulatory subunit RIIa of cAMP-dependent protein kinase encodes an alternate amino-terminal region. FEBS Letters 246:57-64.
  14. Ekanger R, Vintermyr OK, Houge G, Sand TE, Scott JD, Krebs EG, Eikhom TS, Christoffersen T, Ogreid D, and Doskeland SO (1989) The expression of cAMP-dependent protein kinase subunits is differentially regulated during liver regeneration. Journal of Biological Chemistry 264:4374-4389.
  15. Oyen O, Myklebust F, Scott JD, Cadd GG, McKnight GS, Hansson V, and Jahnsen T (1990) Subunits of cyclic adenosine 3′,5′-monophosphate-dependent protein kinase show differential and distinct expression patterns during germ cell differentiation: alternative polyadenylation in germ cells gives rise to unique smaller-sized mRNA species. Biology of Reproduction 43:46-54.
  16. Ludvig N, Ribak CE, Scott JD, and Rubin CS (1990) Immunocytochemical localization of the type II cyclic AMP-dependent protein kinase to postsynaptic structures in the rat brain. Brain Research 520:90-102.
  17. Scott JD, Stofko RE, MacDonald JR, Comer JD, Vitalis EA, and Mangeli J (1990) Type II regulatory subunit dimerization determines the subcellular location of the cAMP-dependent protein kinase. Journal of Biological Chemistry 265:21561-21566.
  18. Wang Y, Scott JD, McKnight GS, and Krebs EG (1991) A constitutively active holoenzyme form of the cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences USA 88:2446-2450.
  19. Carr DW, Stofko RE, Fraser IDC, Bishop SM, Acott TS, Brennan RG, and Scott JD (1991) Interaction of the regulatory subunit (RII) of cAMP-dependent protein kinase with RII-anchoring proteins occurs through an amphipathic helix binding motif. Journal of Biological Chemistry 266:14188-14192.
  20. Scott JD (1991) Cyclic nucleotide-dependent protein kinases. Review. Pharmacology and Therapeutics 50:123-145.
  21. Machida CM, Scott JD, and Ciment G (1991) NGF-induction of the metalloproteinase transin/stromelysin in PC12 cells: involvement of multiple protein kinases. Journal of Cellular Biology 114:1037-1048.
  22. Scott JD and Carr DW (1992) Subcellular localization of the type II cAMP-dependent protein kinase. News in Physiological Sciences 7:143-148.
  23. Stofko-Hahn RE, Carr DW, and Scott JD (1992) A single step purification for recombinant proteins. Characterization of a microtubule associated protein (MAP2) fragment which associates with the type II cAMP-dependent protein kinase. FEBS Letters 302:274-278.
  24. Carr DW, Hausken ZE, Fraser IDC, Stofko-Hahn RE, and Scott JD (1992) Association of the type II cAMP-dependent protein kinase with a human thyroid RII-anchoring protein. Cloning and characterization of the RII-binding domain. Journal of Biological Chemistry 267:13376-13382.
  25. Carr DW and Scott JD (1992) Blotting and band-shifting: techniques for studying protein-protein interactions. TIBS 17:246-251.
  26. Scott JD and Soderling TR (1992) Serine/threonine protein kinases. Current Opinion in Neurobiology 2:289-295.
  27. Carr DW, Stofko-Hahn RE, Fraser IDC, Cone RD, and Scott JD (1992) Localization of the cAMP-dependent protein kinase to the post synaptic density by A-kinase anchoring proteins: characterization of AKAP79. Journal of Biological Chemistry 267:16816-16823.
  28. Scott JD (1993) Cyclic nucleotide-dependent protein kinases. Review. In: Encyclopedia of Pharmacology and Therapeutics 139:137-156.
  29. Carr DW, DeManno DA, Atwood A, Hunzicker-Dunn M, and Scott JD (1993) Follicle-stimulating hormone regulation of A-kinase anchoring protein in granulosa cells. Journal of Biological Chemistry 268:20729-20732.
  30. Coghlan VM, Bergeson SE, Langeberg LK, Nilaver G, and Scott JD (1993) A-kinase anchoring proteins: a key to selective activation of cAMP-responsive events? Molecular and Cellular Biochemistry 127:309-321.
  31. Scott JD and McCartney S (1994) Localization of A-kinase through anchoring proteins. Molecular Endocrinology 8:5-11.
  32. Cheley S, Panchal RG, Carr DW, Scott JD, and Bayley H (1994) Type II regulatory subunits of cAMP-dependent protein kinase and their binding proteins in the nervous system of Aplysia californica. Journal of Biological Chemistry 269:2911-2920.
  33. Coghlan VM, Langeberg LK, Fernandez A, Lamb NJC, and Scott JD (1994) Cloning and characterization of AKAP 95, a nuclear protein that associates with the regulatory subunit of type II cAMP-dependent protein kinase. Journal of Biological Chemistry 269:7658-7665.
  34. Rosenmund C, Carr DW, Bergeson SE, Nilaver G, Scott JD, and Westbrook GL (1994) Anchoring of protein kinase A is required for modulation of AMPA/kainate receptors on hippocampal neurons. Nature 368:853-856.
  35. Hausken ZE, Coghlan VM, Schafer Hastings CA, Reimann EM, and Scott JD (1994) Type II regulatory subunit (RII) of the cAMP-dependent protein kinase interaction with A-kinase anchor proteins requires isoleucines 3 and 5. Journal of Biological Chemistry 269:24245-24251.
  36. Solberg R, Tasken K, Wen W, Coghlan V, Meinkoth JL, Scott JD, Jahnsen T, and Taylor SS (1994) Human regulatory subunit RIß of cAMP-dependent protein kinases: expression, holoenzyme formation and microinjection into living cells. Experimental Cell Research 214:595-605.
  37. Coghlan VM, Perrino BA, Howard M, Langeberg LK, Hicks JB, Gallatin WM, and Scott JD (1995) Association of protein kinase A and protein phosphatase 2B with a common anchoring protein. Science 267:108-112.
  38. McCartney S, Little BM, Langeberg LK, and Scott JD (1995) Cloning and characterization of A-kinase anchor protein 100 (AKAP100): a protein that targets A-kinase to the sarcoplasmic reticulum. Journal of Biological Chemistry 270:9327-9333.
  39. McCartney S, Little BM and Scott JD (1995) Analysis of a novel A-kinase anchoring protein 100, (AKAP 100). Biochem Soc Trans 23:268S.
  40. Coghlan VM, Lester L, and Scott JD (1995) A targeting model for reversible phosphorylation. Advances in Protein Phosphatases 9:51-61.
  41. Coghlan VM, Hausken ZE, and Scott JD (1995) Subcellular targeting of kinases and phosphatases by association with bifunctional anchoring proteins. Biochemical Society Transactions 23:592-595.
  42. Klauck TM and Scott JD (1995) The postsynaptic density: a subcellular anchor for signal transduction enzymes. Cellular Signaling 7:747-757.
  43. Klauck TM, Faux MC, Labudda K, Langeberg LK, Jaken S, and Scott JD (1996) Coordination of three signaling enzymes by AKAP79, a mammalian scaffold protein. Science 271:1589-1592.
  44. Faux MC and Scott JD (1996) Molecular glue: kinase anchoring and scaffold proteins: conferring specificity by location. Cell 85:9-12.
  45. Lester LB, Coghlan VM, Nauert B, and Scott JD (1996) Cloning and characterization of a novel A-kinase anchoring protein: AKAP 220 association with testicular peroxisomes. Journal of Biological Chemistry 271:9460-9465.
  46. Faux MC and Scott JD (1996) More on target with protein phosphorylation. TIBS 21:312-315.
  47. Hausken ZE and Scott JD (1996) Properties of A-kinase anchoring proteins. Biochemical Society Transactions 24:986-991.
  48. Zhang Q, Carr DW, Lerea KM, Scott JD, and Newman SA (1996) Nuclear localization of type II cAMP-dependent protein kinase during limb cartilage differentiation is associated with a novel developmentally regulated A-kinase anchoring protein. Developmental Biology 176:51-61.
  49. Hausken ZE, Dell’Acqua ML, Coghlan VM, and Scott JD (1996) Mutational analysis of the AKAP-binding site on RII: classification of side-chain determinants for anchoring and isoform selective association with AKAPs. Journal of Biological Chemistry 271:29016-29022.
  50. Nauert JB, Klauck TM, Langeberg LK, and Scott JD (1997) Gravin: an autoantigen recognized by myasthenia gravis sera is a kinase scaffold protein. Current Biology 7:52-67.
  51. Dell’Acqua ML and Scott JD (1997) Protein kinase A anchoring. Journal of Biological Chemistry 272:12881-12884.
  52. Scott JD (1997) Dissection of protein kinase and phosphatase targeting interactions. In: Cytoskeletal Regulation of Membrane Function, Society of General Physiologists 50th Annual Symposium, 227-239.
  53. Faux MC and Scott JD (1997) Regulation of the AKAP79-protein kinase C interaction by Ca2+/calmodulin. Journal of Biological Chemistry 272:17038-17044.
  54. Lester LB and Scott JD (1997) Anchoring and scaffold proteins for kinases and phosphatases. In: Recent Progress in Hormone Research, Proceedings of the 1996 Conference, The Endocrine Society 52:409-430.
  55. Gao T, Yatani A, Dell’Acqua ML, Sako H, Green, S.A., Dascal, N., Scott, J.D. and Hosey, M.M. (1997). cAMP-dependent regulation of cardiac L-type Ca2+ channels requires membrane targeting of PKA and phosphorylation of channel subunits.  Neuron 19:185-196.
  56. Burton KA, Johnson BD, Hausken ZE, Westenbroek RE, Idzerda RL, Scott JD, Catterall WA, and McKnight GS (1997) Type II regulatory subunits are not required for the anchoring-dependent modulation of Ca2+ channel activity by cAMP-dependent proteins. Proceedings of the National Academy of Sciences USA 94:11067-11072. PMCID: PMC25142.
  57. Newlon MG, Roy M, Hausken ZE, Scott JD, and Jennings PA (1997) The A-kinase anchoring domain of typeIIa cAMP-dependent protein kinase is highly helical. Journal of Biological Chemistry 272:23637-23644.
  58. Pawson TJ and Scott JD (1997) Signaling through scaffold, anchoring and adaptor proteins. Science 278:2075-2080.
  59. Lester LB, Langeberg LK, and Scott JD (1997) Anchoring of PKA is required for cAMP-mediated insulin secretion. Proceedings of the National Academy of Sciences USA 94:14942-14947. PMCID: PMC25142
  60. Hausken ZE, Coghlan VM, and Scott JD (1998) Overlay, ligand blotting and band-shift techniques to study kinase anchoring. Methods in Molecular Biology, v. 88. From: Protein Targeting Protocols.  Edited by: R.A. Clegg, Humana Press Inc., Totowa, NJ, pp.47-64.
  61. Scott JD and Faux MC (1998) Use of synthetic peptides in the dissection of protein-targeting interactions. Methods in Molecular Biology, v. 88. From: Protein Targeting Protocols. Edited by: R.A. Clegg, Humana Press Inc., Totowa, NJ, pp.161-185.
  62. Dell’Acqua ML, Faux MC, Thorburn J, Thorburn A, and Scott JD (1998) Membrane targeting sequences on AKAP79 bind phosphatidylinositol-4,5-bisphosphate. EMBO Journal 17:2246-2260.
  63. Fraser IDC, Tavalin SJ, Lester LB, Langeberg LK, Westphal AM, Dean RA, Marrion NV, and Scott JD (1998) A novel lipid-anchored A-kinase anchoring protein facilitates cAMP-responsive membrane events. EMBO Journal 17:2261-2272.
  64. Gray PC, Scott JD, and Catterall WA (1998) Regulation of ion channels by cAMP-dependent protein kinase and A-kinase anchoring proteins. Current Opinion in Neurobiology 8:330-334.
  65. Murphy BJ and Scott JD (1998) Functional anchoring of the cAMP-dependent protein kinase. Trends in Cardiovascular Research 8:89-95.
  66. Eide T, Coghlan V, Orstavik S, Holsve C, Solberg R, Skalhegg BS, Lamb NJC, Langeberg L, Fernandez A, Scott JD, Jahnsen T, and Tasken K (1998) Molecular cloning, chromosomal localization and cell cycle-dependent subcellular distribution of the A-kinase anchoring protein, AKAP95. Experimental Cell Research 238:305-316.
  67. Hunzicker-Dunn M, Scott JD, and Carr DW (1998) Regulation of expression of A-kinase anchoring proteins in rat granulosa cells. Biology of Reproduction 58:1496-1502.
  68. Shih M, Lin F, Scott JD, Wang H, and Malbon C (1999) ß2-Adrenergic receptors with protein kinases and phosphatases and the role of Gravin. Journal of Biological Chemistry 274:1588-1595.
  69. Newlon MG, Roy M, Morikis D, Hausken ZE, Coghlan V, Scott JD, and Jennings PA (1999) The molecular basis for protein kinase A anchoring revealed by solution NMR. Nature Structural Biology 6:222-227.
  70. Edwards AS, Faux MC, Scott JD, and Newton AC (1999) Carboxyl-terminal phosphorylation regulates the function and subcellular localization of protein kinase C bII. Journal of Biological Chemistry 274:6461-6468.
  71. Schillace RV and Scott JD (1999) Organization of kinases, phosphatases, and receptor signaling complexes. Journal of Clinical Investigation 103:761-765. PMCID: PMC408155.
  72. Schillace RV and Scott JD (1999) Association of the yype 1 phosphatase with the cAMP dependent protein kinase anchoring protein AKAP220. Current Biology 9:321-324.
  73. Harada H, Becknell B, Matthias W, Mann M, Huang L, Taylor S, Scott JD, and Korsmeyer S (1999) Phosphorylation and inactivation of BAD by mitochondrial anchored protein kinase. Molecular Cell 3:413-422.
  74. Scott JD, Dell’Acqua ML, Fraser IDC, Tavalin SJ, and Lester LB (1999) Coordination of cAMP signaling events through PKA anchoring. In: Hormone and Signaling. San Diego: Academic Press 2:175-207.
  75. Colledge M and Scott JD (1999) AKAPs: Form structure to function. Trends in Cell Biology 9:216-221.
  76. Westphal R, Tavalin SJ, Lin JW, Alto NM, Fraser IDC, Langeberg LK, Sheng M, and Scott JD (1999) Regulation of NMDA receptors by an associated phosphatase-kinase signaling complex. Science 285:93-96.
  77. Tavalin SJ, Westphal RS, Colledge M, Langeberg LK, and Scott JD (1999) The molecular architecture of neuronal kinase/phosphatase signaling complexes. Biochemical Society Transactions 27:539-542.
  78. Kapiloff MS, Schillace R, Westphal AM, and Scott JD (1999) mAKAP: An A-kinase anchoring protein targeted to the nuclear membrane of differentiated myocytes. Journal of Cell Science 112: 2725-2736.
  79. Fraser IDC and Scott JD (1999) Modulation of Ion Channels: A “current” view of AKAPs. Neuron 23:423-426.
  80. Faux MC, Rollins EN, Edwards AS, Langeberg LK, Newton AC, and Scott JD (1999) Mechanism of A-kinase-anchoring protein 79 (AKAP79) and protein kinase C interaction. Biochemical Journal 343:443-452.
  81. Trotter KW, Fraser IDC, Scott GK, Stutts MJ, Scott JD, and Milgram SL (1999) Alternative splicing regulates the subcellular localization of AKAP18 isoforms. Journal of Cell Biology 147:1481-1492. PMCID: PMC2174236.
  82. Carr DW, Culter RE, Cottom JE, Salvador LM, Fraser IDC, Scott JD, and Hunzicker-Dunn M (1999) Identification of cAMP-dependent protein kinase holoenzymes in preantral and preovulatory-follicle-enriched ovaries, and their association with A-kinase-anchoring proteins. Biochemical Journal 344:613-623.
  83. Edwards AE and Scott JD (2000) A-Kinase anchoring proteins: PKA and beyond. Current Opinions in Cell Biology 12:217-221.
  84. Scott JD and Pawson TJ (2000) Cell communications: “the inside story”. Scientific American 282:72-79.
  85. Fraser IDC, Cong M, Kim J, Rollins EN, Daaka Y, Lefkowitz RJ, and Scott JD (2000) Assembly of an AKAP/beta2 -adrenergic receptor signaling complex facilitates receptor phosphorylation and signaling. Current Biology 10:409-412.
  86. Diviani D, Langeberg LK, Doxsey SJ, and Scott JD (2000) Pericentrin anchors protein kinase A at the centrosome through a novel RII binding domain. Current Biology 10:417-420.
  87. Sim ATR and Scott JD (2000) Targeting of PKA, PKC and protein phosphatases to cellular microdomains. Cell Calcium 5:209-217.
  88. Dodge K and Scott JD (2000) AKAP79 and the evolution of the AKAP model. FEBS Letters 476:58-61.
  89. Colledge M, Dean RA, Scott GK, Langeberg LK, Huganir RL, and Scott JD (2000) Targeting of PKA to glutamate receptors through a MAGUK-AKAP complex. Neuron 27:107-119.
  90. Westphal RS, Soderling SH, Alto NM, Langeberg LK, and Scott JD (2000) Scar/WAVE-1, a Wiskott-Aldrich syndrome protein, assembles an actin associated serine/theronine and tyrosine kinase scaffold. EMBO Journal 19:4589-4600. PMCID: PMC302050
  91. Lin D, Edwards AE, Fawcett JP, Mbamalu G, Scott JD, and Pawson TJ (2000) Mammalian PAR-3/PAR-6 multi-protein complex implicated in Cdc42/Rac1 and aPKC signaling and in cell polarity. Nature Cell Biology 2:540-547.
  92. Diviani D and Scott JD (2001) AKAP signaling complexes at the cytoskeleton. Journal of Cell Science 114:1431-1437.
  93. Lester LB, Faux MC, Nauert JB, and Scott JD (2001) Reversible phosphorylation of pancreatic beta cell synapsin I: role of targeted PKA and protein phosphatase 2B. Endocrinology 142:1218-1227.
  94. Newlon MG, Roy M, Morikis D, Carr D, Westphal R, Scott JD, and Jennings PA (2001) The molecular basis of PKA anchoring revealed by the solution structures of two AKAP-peptide complexes. EMBO Journal 20:1651-1662.
  95. Potet F, Scott JD, Escande D, and Baro I (2001) AKAP Proteins anchor cAMP-dependent protein kinase to KvLQT1/IsK tandem. American Journal of Physiology 280:2038-2045.
  96. Cong M, Perry SJ, Lin FT, Fraser ID, Hu LA, Chen W, Pitcher JA, Scott JD, Lefkowitz RJ (2001) Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein AKAP79. Journal of Biological Chemistry 276:15192-15199 PMID: 11278469.
  97. Schillace RV, Voltz JW, Sim AT, Shenolikar S, and Scott JD (2001) Multiple interactions within the AKAP220 signaling complex contribute to PP1 regulation. Journal of Biological Chemistry 276:12128-12134.
  98. Dodge KL, Khouangsathiene S, Kaplioff MS, Mouton R, Vill EV, Houslay MD, Langeberg LK, and Scott JD (2001) mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module. EMBO Journal 20:1921-1930. PMCID: PMC125429
  99. Jo I, Ward DT, Baum MA, Scott JD, Coghlan VM, Hammond TG, and Harris HW (2001) AQP2 is a substrate for the endogenous calcineurin activity within an inner medullary AKAP-signaling complex. American Journal of Physiology 281:958-965.
  100. Perkins G, Wang L, Huang L, Humphries K, Yao VJ, Martone M, Deernick TJ, Violin JD, Smith D, Newton A, Scott JD, Taylor SS, and Ellisman MH (2001) PKA, PKC, and AKAP Localization in and around the neuromuscular junction. BMC Neuroscience 2:17-27. PMCID: PMC59892.
  101. Diviani D, Soderling JA, and Scott JD (2001) AKAP-Lbc anchors PKA and nucleates Ga12 selective Rho mediated stress fiber formation. Journal of Biological Chemistry 276:44247-44257.
  102. Scott JD (2002) Signal transduction according to the book. Review. Nature Cell Biology 4:E14.
  103. Smith FD and Scott JD (2002) Signaling complexes: junctions on the intracellular information super highway. Current Biology 12:32-40.
  104. Michel J and Scott JD (2002) AKAP mediated signal transduction. Annual Review in Pharmacology 42:235-257.
  105. Tavalin SJ, Colledge M, Hell JW, Huganir RL, and Scott JD (2002) Regulation of Glur1 by the AKAP79 signaling complex shares properties with LTD. Journal of Neuroscience 22:3044-3051.
  106. Morikis D, Roy M, Newlon MG, Scott JD, and Jennings PA (2002) Electrostatic properties of the structure of the docking and dimerization domain of protein kinase AIIa. European Journal of Biochemistry 269: 2040-2051.
  107. Bauman AL and Scott JD (2002) Kinase and phosphatase anchoring proteins: harnessing the dynamic duo. Nature Cell Biology 4:203-206.
  108. Altier C, Dubel SJ, Barrere C, Jarvis SE, Stotz SC, Spaetgens RL, Scott JD, Cornet V, Waard MD, Zamponi GW, Nargeot J, and Bourinet E (2002) Trafficking of L-type calcium channels mediated by the postsynaptic scaffolding protein AKAP79. Journal of Biological Chemistry 277:33598-33603.
  109. Alto NM, Soderling J, and Scott JD (2002) Rab32 is an A-Kinase anchoring protein and participates in mitochondrial dynamics. Journal of Cell Biology 158:659-668. PMCID: PMC2174006
  110. Soderling SH, Binns KM, Wayman GA, Davee SM, Ong SH, Pawson TJ, and Scott JD (2002) The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling. Nature Cell Biology 4:970-975.
  111. Dell’Acqua ML, Dodge KL, Tavalin SJ, and Scott JD (2002) Mapping the protein phosphatase 2-B anchoring site on AKAP79: binding and inhibition of phosphatase activity are mediated by residues 315-360. Journal of Biological Chemistry 277:48796-48802.
  112. Alto NM, Michel J, Dodge KL, Langeberg LK, and Scott JD (2002) Intracellular targeting of protein phosphatases. Diabetes 51:385-388.
  113. Scott JD (2003) A-kinase-anchoring proteins and cytoskeletal signalling events. Biochemical Society Transactions 31:87-89.
  114. Brandon NJ, Jovanovic JN, Colledge M, Kittler JT, Brandon JM, Scott JD, and Moss SJ (2003) A-Kinase anchoring protein 79/150 facilitates the phosphorylation of GABAA receptors by cAMP-dependent protein kinase via selective interaction with receptor b Molecular and Cellular Neuroscience 22:1:87-97.
  115. Soderling SH, Langeberg LK, Soderling JA, Davee SM, Raber J, and Scott JD (2003) Loss of WAVE-1 causes sensorimotor retardation and reduced learning and memory in mice. Proceedings of the National Academy of Sciences USA 100:1723-1728.
  116. Alto NM, Soderling SH, Hoshi N, Langeberg LK, Fayos R, Jennings PA, and Scott JD (2003) Bioinformatic design of AKAP “in-silico”: a potent and selective peptide antagonist of type II protein kinase A anchoring. Proceedings of the National Academy of Sciences USA 100:4445-4450.
  117. Hoshi N, Zhang J, Omaki M, Takeuchi T, Yokoyama S, Wanaverbecq N, Langeberg LK, Yoneda Y, Scott JD, Brown DA, and Higashida H (2003) AKAP150 signaling complex promotes suppression of the M-current by muscarinic agonists. Nature Neuroscience 6: 564-571. PMCID: PMC3941299
  118. Fayos R, Melacini G, Newlon MG, Burns L, Scott JD, and Jennings PA (2003) Induction of flexibility through protein-protein interactions. Journal of Biological Chemistry 278:18581-18587.
  119. Scott JD (2003) Protein proximity interactions. Handbook of Cell Signaling 171:293-297.
  120. Langeberg LK and Scott JD (2003) AKAP signaling complexes: the combinatorial assembly of signal transduction units. Handbook of Cell Signaling 186:387-392.
  121. Ruehr ML, Russell MA, Ferguson DG, Bhat M, Ma J, Damron DS, Scott JD, and Bond M (2003) Targeting of protein kinase A by muscle A kinase-anchoring protein (mAKAP) regulates phosphorylation and function of the skeletal muscle ryanodine receptor. Journal of Biological Chemistry 278:24831-24836.
  122. Carnegie GK and Scott JD (2003) A-kinase anchoring proteins and neuronal signaling mechanisms. Genes & Development 17:1557-1568.
  123. Colledge M, Snyder EM, Crozier RA, Soderling JA, Jin Y, Langeberg LK, Lu H, Bear MF, and Scott JD (2003) Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression. Neuron 40:595-607.
  124. Dodge KL and Scott JD (2003) Calcineurin anchoring and cell signaling. Biochemical and Biophysical Research Communications 311:1111-1115.
  125. Bauman AL, Goehring AS, and Scott JD (2004) Orchestration of synaptic plasticity through AKAP signaling complexes. Journal of Neuropharmacology 3:299-310.
  126. Alto NM and Scott JD (2004) The role of A-kinase anchoring proteins in cAMP-mediated signal transduction pathways. Cell Biochemistry & Biophysics 40:201-208.
  127. Salvador LM, Flynn MP, Avila J, Reierstad S, Maizels ET, Alam H, Park Y, Scott JD, Carr DW, and Hunzicker-Dunn M (2004) Neuronal microtubule-associated protein 2D is a dual A-kinase anchoring protein expressed in rat ovarian granulosa cells. Journal of Biological Chemistry 279:27621–27632.
  128. Carlisle Michel JJ, Dodge KL, Wong W, Mayer NC, Langeberg LK, and Scott JD (2004) PKA phosphorylation of PDE4D3 facilitates recruitment of the mAKAP signalling complex. Biochemical Journal 381:587-592.
  129. Jin J, Smith FD, Stark C, Wells CD, Fawcett JP, Kulkarni S, Metalnikov P, O’Donnell P, Taylor P, Taylor L, Zougman A, Woodgett JR, Langeberg LK, Scott JD, and Pawson TJ (2004) Proteomic, functional and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. Current Biology 14:1436-1450.
  130. Carnegie GK, Smith FD, McConnachie G, Langeberg LK, and Scott JD (2004) AKAP-Lbc nucleates a protein kinase D activation scaffold. Molecular Cell 15:889-899.
  131. Langeberg LK and Scott JD (2004) A-kinase anchoring proteins, in Encyclopedia of Biological Chemistry (W.J. Lennarz & M.D. Lane, eds), Elsevier, Oxford, Vol. 1, pp. 64-67.
  132. Wong W and Scott JD (2004) AKAP signalling complexes: focal points in space and time. Nature Reviews Cell Biology 5:959-970.
  133. Li Y, Keller DM, Scott JD, and Lu H (2005) CK2 phosphorylates SSRP1 and inhibits its DNA-binding activity. Journal of Biological Chemistry 280:11869-11875.
  134. Snyder EM, Colledge M, Crozier RA, Chen WS, Scott JD, and Bear MF (2005) Role for A kinase anchoring proteins (AKAPs) in glutamate receptor trafficking and long-term synaptic depression. Journal of Biological Chemistry 280:16962-16968.
  135. Baillie GS, Scott JD, and Houslay MD (2005) Compartmentalization of phosphodiesterases and protein kinase A: opposites attract. FEBS Letters 579:3264-3270.
  136. Pawson TJ and Scott JD (2005) Protein phosphorylation in signaling – 50 years and counting. Trends in Biochemical Sciences 30:286-290.
  137. Langeberg LK and Scott JD (2005) AKAPs at a glance. Journal of Cell Science 118:3217-3220.
  138. Gorski J, Gomez L, Scott JD, and Dell’Acqua M (2005) Association of an AKAP signaling scaffold with cadherin adhesion molecules in neurons and epithelial cells. Molecular Biology of the Cell 16:3574-3590.
  139. Dodge-Kafka KL, Soughayer J, Pare GC, Carlisle Michel JJ, Langeberg LK, Kapiloff MS, and Scott JD (2005) The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways. Nature 437:574-578. PMCID: PMC1636584
  140. Hoshi N, Langeberg LK, and Scott JD (2005) Distinct enzyme combinations in AKAP signaling complexes permit functional diversity. Nature Cell Biology 7:1066-1073.
  141. Michel JJ, Townley IK, Dodge-Kafka KL, Zhang F, Kapiloff MS, and Scott JD (2005) Spatial restriction of PDK1 activation cascades by anchoring to mAKAPa. Molecular Cell 20:661-672.
  142. Soderling SH and Scott JD (2006) WAVE signalling-from biochemistry to biology. Biochemical Society Transactions 34:73-76.
  143. Dodge-Kafka KL, Langeberg LK, and Scott JD (2006) Compartmentalization of cyclic nucleotide signaling in the heart: the role of A-kinase anchoring proteins. Circulation Research 98:993-1001.
  144. Willoughby D, Wong W, Schaack J, Scott JD, and Cooper DMF (2006) An anchored PKA and PDE4 complex regulates sub-plasmalemmal cAMP dynamics. EMBO Journal 25:2051-2061. PMCID: PMC1462982
  145. Hundsrucker C, Krause G, Beyermann M, Prinz A, Zimmermann B, Diekmann O, Lorenz D, Stefan E, Nedvet-sky P, Dathe M, Christian F, McSorley T, Krause E, McConnachie G, Herberg FW, Scott JD, Rosenthal W, and Klussmann E (2006) High-affinity AKAP18δ-protein kinase A interaction yields novel protein kinase A anchoring disruptor peptides. Biochemical Journal 396:297-306.
  146. Hoshi N and Scott JD (2006) Contextual utilization of enzymes in discrete AKAP79/150 signalling complexes. European Journal of Cell Biology 85:621-622.
  147. Smith FD and Scott JD (2006) Anchored cAMP signaling: onward and upward – a short history of compartmentalized cAMP signaling transduction. European Journal of Cell Biology 85:585-592.
  148. Smith FD, Langeberg LK, and Scott JD (2006) The where’s and when’s of kinase anchoring. Trends in Biochemical Science 31:316-323.
  149. Kim Y, Sung JY, Ceglia I, Lee K, Ahn J, Halford JM, Kim A, Kwak SP, Park JB, Ryu SH, Schenck A, Bardoni G, Mandel J, Scott JD, Nairn AC, and Greengard P (2006) Phosphorylation of WAVE-1 regulates actin polymerization and dendritic spine morphology. Nature 442:814-817.
  150. Bauman AL, Soughayer J, Nguyen BT, Willoughby D, Wong W, Hoshi N, Langeberg LK, Cooper DMF, Dessauer CW, and Scott JD (2006) Dynamic regulation of cAMP synthesis through anchored PKA/adenylyl cyclase V/VI complexes. Molecular Cell 23:925-931. PMCID: PMC3941446
  151. Carlson CR, Lygren B, Berge T, Hoshi N, Wong W, Tasken K, and Scott JD (2006) Delineation of type I protein kinase A-selective signaling events using an RI anchoring disruptor (RIAD). Journal of Biological Chemistry 281:21535-21545.
  152. McConnachie G, Langeberg LK, and Scott JD (2006) AKAP signaling complexes: getting to the heart of the matter. Trends in Molecular Medicine 12:317-23.
  153. Scott JD (2006) Compartmentalized cAMP signaling: a personal perspective. Biochemical Society Transactions 34:465-467.
  154. Gardner LA, Tavalin SJ, Goehring A, Scott JD, and Bahouth SW (2006) AKAP79-mediated targeting of the cyclic AMP-dependent protein kinase to the ß1-adrenergic receptor promotes recycling and functional resensitization of the receptor. Journal of Biological Chemistry 281:33537-53.
  155. Gold MG, Lygren B, Dokurno P, Hoshi N, McConnachie G, Tasken K, Carlson CR, Scott JD, Barford D (2006) Molecular basis of AKAP specificity for PKA regulatory subunits. Molecular Cell 24:383-95.
  156. Stokka AJ, Gesellchen F, Carlson CR, Scott JD, Herberg FW, and Tasken K (2006) Characterization of A-kinase anchoring disruptors using a solution based assay. Biochemical Journal 400:493-9.
  157. Soderling SH, Guire ES, Kaech S, White J, Zhang F, Schutz K, Langeberg LK, Banker G, Raber J, and Scott JD (2007) A WAVE-1 and WRP signaling complex regulates spine density, synaptic plasticity and memory. Journal of Neuroscience 27:355-365.
  158. Beene DL and Scott JD (2007) A-kinase anchoring proteins take shape. Current Opinion in Cell Biology 19:192-198. PMCID: PMC3521038
  159. Goehring AS, Pedroja BS, Hinke SA, Langeberg LK, and Scott JD (2007) MyRIP anchors protein kinase A to the exocyst complex. Journal of Biological Chemistry 282:33155-33167. PMCID: PMC3508720
  160. Gold MG, Smith FD, Scott JD, and Barford D (2008) AKAP18 contains a phosphoesterase domain that binds AMP. Journal of Molecular Biology 375(5):1329-1343. PMCID: PMC3188456
  161. Kussman E and Scott JD (2008) Protein-Protein Interactions as New Drug Targets: Introduction In: E. Klussman, J.D. Scott, editors. Handbook of Experimental Pharmacology Berlin Heidelberg: Springer-Verlag; 2008. pp. 483-503.
  162. Langeberg LK and Scott JD (2008) AKAP transduction units: context-dependent assembly of signaling complexes. In: R. Bradshaw, E. Dennis, editors. Handbook of Cell Signaling. 2nd ed. Oxford: Academic Press; 2008. pp. 1337-1342.
  163. Gold M and Scott JD (2008) Protein proximity interactions. In: R. Bradshaw, E. Dennis, editors. Handbook of Cell Signaling 2nd ed. Oxford: Academic Press; 2008. pp. 1245-1246.
  164. Tunquist BJ, Hoshi N, Guire ES, Zhang F, Müllendorff K, Langeberg LK, Raber J, and Scott JD (2008) Loss of AKAP150 perturbs distinct neuronal processes in mice. Proceedings of the National Academy of Sciences USA 105:12557-12562. PMCID: PMC2527950
  165. Piggott LA, Bauman AL, Scott JD, and Dessauer CW (2008) The A-kinase anchoring protein Yotiao binds and regulates adenylyl cyclase in brain. Proceedings of the National Academy of Sciences USA USA 105:13835-13840. PMCID: PMC2544540
  166. Carnegie GK, Soughayer J, Smith FD, Pedroja BS, Zhang F, Diviani D, Bristow MR, Kunkel MT, Newton AC, Langeberg LK, and Scott JD (2008) AKAP-Lbc mobilizes a cardiac hypertrophy signaling pathway. Molecular Cell 32:169-179. PMCID: PMC3169907
  167. Jarnæss E, Ruppelt A, Stokka A, Lygren B, Scott JD, and Taskén K (2008) Dual-Specificity A-Kinase Anchoring Proteins (AKAPs) Contain An Additional Binding Region That Enhances Targeting of PKA Type I1. Journal of Biological Chemistry 283: 33708-33718. PMCID: PMC2586281
  168. Paulucci-Holthauzen AA, Vergara LA, Bellot LJ, Canton D, Scott JD, and O’Connor KL (2008) Spatial distribution of PKA activity during cell migration is mediated by A-kinase anchoring protein AKAP Lbc. Journal of Biological Chemistry. 284:5956-5967. PMCID: PMC2645839
  169. Wong W, Goehring AS, Kapiloff MS, Langeberg LK, and Scott JD (2008) mAKAP compartmentalizes oxygen-dependent control of HIF-1α. Science Signaling 1:84-92. PMCID: PMC2828263
  170. Carnegie GK, Means CK, and Scott JD (2009) A-Kinase Anchoring Proteins: From Protein Complexes to Physiology and Disease. IUBMB Life 61:394-406. PMCID: PMC2682206
  171. Smith FD, Langeberg LK, and Scott JD (2009) Spatial and temporal control of cell signaling by A-kinase Anchoring Proteins. In: Signal Transduction: Pathways, Mechanisms and Diseases   (A. Sitaramayya, editor). Springer-Verlag,  Berlin Heidelberg. 2009 pp. 183-197.
  172. Jarnæss E, Stokka AJ, Kvissel A-K, Skålhegg BS, Torgersen KM, Scott JD, Carlson CR, and Taskén K (2009) Splicing factor arginine/serine-rich 17A (SFRS17A) is an A-Kinase anchoring protein that targets protein kinase A to splicing factor compartments. Journal of Biological Chemistry 284:35145-35164. PMCID: PMC2787376
  173. Scott JD and Pawson T (2009) Cell Signaling in Space and Time: Where Proteins Come Together and When They’re Apart. Science 326:1220-1224. PMCID: PMC3041271
  174. Hoshi N, Langeberg LK, Gould CM, Newton AC, and Scott JD (2010) Interaction with AKAP79 modifies the cellular pharmacology of PKC. Molecular Cell 37:541-550. PMCID: PMC3014287
  175. Scott JD and Santana LF (2010) A-Kinase Anchoring Proteins: getting to the heart of the matter. Circulation 121:1264-1271. PMCID: PMC3014256
  176. Hinke SA, Canton DA, and Scott JD (2010) Control of Insulin Secretin by Phosphorylation-Dependent Signalling Networks. In: Islet Transplantation: Biology, Immunology and Clinical Applications. (ed. Kandeel FR). Springer, New York, NY.  (in press)
  177. Navedo MF, Cheng EF, Yuan C, Votaw S, Molkentin JD, Scott JD, and Santana LF (2010) Increased coupled gating of L-type Ca2+ channels during hypertension and Timothy Syndrome. Circulation Research 106:748-756. PMCID: PMC2834417
  178. Catterall WA and Scott JD (2010) Retrospective. Edwin G. Krebs (1918-2009). Science 327:537. PMID: 20110494
  179. Efendiev R, Samelson BK, Nguyen B, Phatarpekar P, Baameur F, Scott JD, and Dessauer CW (2010) AKAP79 Interacts with Multiple Adenylyl Cyclase (AC) Isoforms and Scaffolds AC 5 and 6 to AMPA Receptors. Journal of Biological Chemistry 285:14450-14458. PMCID: PMC2863235
  180. Welch EJ, Jones BW, and Scott JD (2010) Networking with AKAPs: Context-dependent Regulation of Anchored Enzymes. Molecular Interventions 10:86-97. PMCID: PMC2895371
  181. Smith, F.D., Langeberg, L.K., Scott, J.D. (2010). Spatial and Temporal Control of Cell Signaling by A-Kinase Anchoring Proteins. In: Sitaramayya, A. (eds) Signal Transduction: Pathways, Mechanisms and Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-02112-1_10
  182. Scott JD (2010) Edwin G. Krebs(1918-2009) Our Beloved “Reluctant” Biochemist. ASBMB Today January:11-15.
  183. Logue JS and Scott JD (2010) Organizing Signal Transduction through A-Kinase Anchoring Proteins (AKAPs). FEBS Journal 277:4370-4375. published online:  30 SEP 2010  PMCID: PMC3014294
  184. Pawson C and Scott JD (2010) Signal Integration through blending, bolstering and bifurcating of intracellular information. Nature Structure Molecular Biology 17:653-658. PMCID: PMC3086636
  185. Bui M, Gilady SY, Fitzsimmons REB, Lynes EM, Gesson K, Alto N, Strack S, Scott JD, and Simmen T (2010) Rab32 modulates apoptosis onset and mitochondria-associated membrane (MAM) properties. Journal of Biological Chemistry 285:31590-31602. PMCID: PMC2951233
  186. Por ED, Samelson BK, Scott JD, and Jeske NA (2010) PP2B/calcineurin-mediated desensitization of TRPV1 channels does not require AKAP150. Biochemical Journal 432:549-556 PMCID: PMC3050517
  187. Canton DA and Scott JD (2010) Chk-ing in and Chk-ing out: Kinase Compartmentalization Comes to Checkpoint Control. Molecular Cell 40:1-2. PMCID: PMC3014293
  188. Smith FD, Langeberg LK, Cellurale C, Morrison DK, Pawson T, Davis RJ, and Scott JD (2010) AKAP-Lbc enhances cAMP control of the ERK1/2 cascade. Nature Cell Biology 12:1242-1249. PMCID: PMC3042953
  189. Lyssand JS, Whiting JL, Lee K-S, Kastl R, Wacker JL, Bruchas M, Miyatake M, Langeberg LK, Chavkin C, Scott JD, Gardner R, Adams ME, and Hague C (2010) α-Dystrobrevin-1 recruits α-Catulin to the α1D-Adrenergic Receptor/DAPC Signalosome. Proceedings of the National Academy of Sciences USA 107:21854-21859. PMCID: PMC3003112
  190. Wanichawan P, Louch WE, Hortemo KH, Austbø B, Lunde PK, Scott JD, Sejersted O, and Carlson CR (2011) Full length cardiac Na2+ – Ca2+ exhanger (NCX1) protein is not phosphorylated by protein kinase A (PKA). American Journal of Physiology – Cell Physiology 300:C989-997. PMCID: PMC3093950
  191. Perino A, Ghigo A, Ferrero E, Morello F, Santulli G, Baillie G, Damilano F, Dunlop AJ, Pawson C, Walser R, Levi R, Altruda F, Silengo L, Langeberg LK, Neubauer G, Heymans S, Lembo G, Wymann MP, Wetzker R, Houslay MD, Iaccarino G, *Scott JD, and *Hirsch E (co-corresponding authors) (2011) Integrating cardiac PIP3 and cAMP signaling through a PKA anchoring function of p110γ. Molecular Cell 42:84-95. PMCID: PMC3265115
  192. Smith FD, Langeberg LK, and Scott JD (2011) Plugging PKA into ERK scaffolds. Cell Cycle 10:731-732. PMCID: PMC3322337
  193. Gold M, Stengel F, Nygren P, Weisbrod CR, Bruce JE, Robinson C, Barford D, Scott JD (2011) Architecture and Dynamics of the AKAP79 Signaling Complex. Proceedings of the National Academy of Sciences USA 108:6426-6431. PMCID: PMC3081024
  194. Carnegie GK and Scott JD (2011) A-Kinase Anchoring Protein (AKAP). In: Encyclopedia of Signalling Molecules Choi S, editor. Encyclopedia of Signaling Molecules: Springer New York; 2012. pp. 89-96.
  195. Day ME, Gaietta GM, Sastri M, Koller A, Mackey MR, Scott JD, Perkins GA, Ellisman MH, and Taylor SS (2011) Isoform-specific targeting of PKA to multivesicular bodies. Journal of Cell Biology 193:347-363. PMCID: PMC3080257
  196. Logue JS, Whiting JL, Tunquist BJ, Langeberg LK, and Scott JD (2011) Anchored PKA Recruitment of Active RAC. Journal of Biological Chemistry 286:22113-22121. PMCID: PMC3121355
  197. Smith FD, Samelson BK, and Scott JD (2011) Discovery of cellular substrates for Protein Kinase A by a peptide array screening protocol. Biochemical Journal 438:103-110. PMCID: PMC3292260
  198. Logue JS, Whiting JL, and Scott JD (2011) Sequestering Rac with PKA confers cAMP control of cytoskeletal remodeling. Small GTPases 2:173-176. PMCID: PMC3136949
  199. Cheng EP, Yuan C, Navedo MF, Dixon RE, Scott JD, and Santana LF (2011) Restoration of normal L-type Ca2+ channel function during Timothy syndrome by ablation of an anchoring protein. Circulation Research 109:255-261. PMCID: PMC3151468
  200. Edwards HV, Scott JD, and Baillie G (2011) PKA phosphorylation of the small heat shock protein Hsp20 enhances its cardioprotective effects. Biochemical Society Transactions 40:210-214. PMCID: PMC3269834
  201. Logue JS, Whiting JL, Tunquist BJ, Sacks DB, Langeberg LK, Wordeman L, and Scott JD (2011) AKAP220 Organizes Signaling Elements that Impact Cell Migration. Journal of Biological Chemistry 286:39269-39281. PMCID: PMC3234751
  202. Means CK, Lygren B, Langeberg LK, Jain A, Dixon RE, Vega AL, Gold MG, Petrosyan S, Taylor SS, Murphy AN, Ha T, Santana LF, Taskén K, and Scott JD (2011) An entirely specific type I A-kinase anchoring protein that can sequester two molecules of PKA at mitochondria. Proceedings of the National Academy of Sciences USA 108:E1227-E1235. PMCID: PMC3228425
  203. Gold M, Reichow SL, O’Neal SE, Weisbrod CR, Langeberg LK, Bruce JE, Gonen T, and Scott JD (2012) AKAP2 anchors PKA with aquaporin-0 to support ocular lens transparency. EMBO Molecular Medicine 4:15-26. PMCID: PMC3272850
  204. Kosenko A, Kang S, Smith IM, Greene DL, Langeberg LK, Scott JD, and Hoshi N (2012) Coordinated signal integration at the M-type potassium channel upon muscarinic stimulation. EMBO Journal 31:3147-3156. PMCID: PMC3400014
  205. Wang B, Means CK, Yang Y, Mamonova T, Bisello A, Altschuler DL, Scott JD, and Friedman PA (2012) Ezrin anchored PKA Coordinates Phosphorylation-dependent Disassembly of a NHERF-1 Ternary Complex to Regulate Hormone-sensitive Phosphate Transport. Journal of Biological Chemistry 287:24148-24163. PMCID: PMC3397842
  206. Altier C, Dubel SJ, Barrere C, Jarvis SE, Stotz SC, Scott JD, Nargeot J, Zamponi GW, and Bourinet E (2012) AKAP79 modulation of L-type channels involves disruption of intramolecular in the Cav2 subunit. Channels 6:157-165. PMCID: PMC3431589
  207. Scott JD and Newton AC (2012) Shedding light on local kinase activation. BMC Biology 10:61. PMCID: PMC3398854
  208. Perino A, Ghigo E, Scott JD, and Hirsch E (2012) Anchoring Proteins as Regulators of Signaling Pathways. Circulation Research 111:482-492. PMCID: PMC3508715
  209. Edwards HV, Scott JD, and Baillie G (2012) The A-kinase anchoring protein AKAP-Lbc facilitates cardioprotective PKA phosphorylation of Hsp20 on Ser(16). Biochem Journal 446:437-443. PMCID: PMC3498943.
  210. Scott JD, Dessauer CW, and Taskén K (2013) Creating order from chaos: Cellular regulation by kinase anchoring. Annual Review of Pharmacology and Toxicology 53:187-210. PMCID: PMC PMC3540170
  211. Canton DA, Keene CD, Swinney K, Langeberg LK, Nguyen V, Pelletier L, Pawson T, Wordeman L, Stella N, and Scott JD (2012) Gravin is a transitory effector of the polo-like kinase 1 during cell division. Molecular Cell 48:547-559. PMCID: PMC3513578.
  212. Hinke SA, Navedo MF, Ulman A, Whiting JL, Nygren P, Tian G, Jimenez-Caliani AJ, Langeberg LK, Cirulli V, Tengholm A, Dell’Acqua ML, Santana LF, and Scott JD (2012) Anchored Phosphatases Modulate Glucose Homeostasis. EMBO Journal 31:3991-4004. PMCID: PMC3474922
  213. Jones BW, Brunet S, Gilbert M, Nichols B, Su T, Westenbroek RE, Scott JD, Catterall WA, and McKnight GS (2012) Cardiomyocytes from AKAP7 Knockout Mice Respond Normally to Adrenergic Stimulation. Proceedings of the National Academy of Sciences USA 109:17099-17104. PMCID: PMC3479465.
  214. Havekes R, Canton DA, Park AJ, Huang T, Nie T, Day JP, Guercio LA, Grimes Q, Luczak V, Gelman I, Baillie G, Scott JD, and Abel T (2012) Gravin orchestrates Protein Kinase A and β2-adrenergic receptor signaling critical for synaptic plasticity and memory. J Neurosci 32:18137-18149. PMCID: PMC3533251.
  215. Smith FD and Scott JD (2013) A-kinase-anchoring protein-Lbc connects stress signaling to cardiac hypertrophy. Mol Cell Biol 33:2-3. PMCID: PMC3536311.
  216. Canton DA and Scott JD (2013) Anchoring proteins encounter mitotic kinases. Cell Cycle 12:863-864. PMCID: PMC3637338.
  217. Gold MG, Fowler DM, Means CK, Pawson CT, Stephany JJ, Langeberg LK, Fields S, and Scott JD (2013) Engineering A-Kinase Anchoring Protein-selective regulatory subunits of Protein Kinase A through structure-based phage selection. Journal of Biological Chemistry 288:17111-17121. PMCID: PMC3682517
  218. Matt U, Sharif O, Martins R, Furtner T, Langeberg LK, Gawish R, Elbau I, Zivkovic A, Lakovits K, Oskolkova O, Doninger B, Vychytil A, Perkmann T, Schabbauer G, Binder C, Bochkov V, Scott JD, and Knapp S (2013) WAVE-1 mediates suppression of phagocytosis by phospholipid-derived DAMPs. Journal of Clinical Investigation 123:3014-3024. PMCID: PMC3696563.
  219. Smith FD and Scott JD (2013) Scaffolding proteins: not such innocent bystanders. Current Biology 23:R515-R517. PMCID: PMC3924780.
  220. Gold MG, Gonen T, and Scott JD (2013 ) Local cAMP Signaling in Disease at a Glance. Journal of Cell Science 126:4537-4543. PMCID: PMC3795333
  221. Scott JD (2013) Tony Pawson 1952-2013. Nat Struct Mol Biol. 20:1146.
  222. Heldin C-H and Scott JD (2013) Tony Pawson 1952-2013. Nature Cell Biology 15:1143
  223. Smith FD, Reichow SL, Esseltine J, Shi D, Langeberg LK, Scott JD, and Gonen T (2013) Intrinsic disorder within an AKAP-Protein kinase A complex guides local substrate phosphorylation. eLife. 2:e01319. PMCID: PMC3814001
  224. Esseltine J and Scott JD (2013) AKAP signaling complexes: pointing towards the next generation of therapeutic targets? Trends Pharmacological Sciences 34:648-655. PMCID: PMC3879114.
  225. Pruneda JN, Smith FD, Daurie A, Swaney DL, Villén J, Scott JD, Stadnyk AW, Le Trong I, Stenkamp RE, Klevit RE, Rohde JR, and Brzovic PS (2014) E2~Ub conjugates regulate kinase activity of Shigella effector OspG during pathogenesis. EMBO Journal 33:437-449. PMCID: PMC3989626
  226. Nystoriak MA, Nieves-Cintron M, Nygren PJ, Hinke SA, Nichols CB, Chen CY, Puglisi JL, Izu LT, Bers DM, Dell’acqua ML, Scott JD, Santana LF, and Navedo MF (2014) AKAP150 Contributes to Enhanced Vascular Tone by Facilitating BKCa Channel Remodeling in Hyperglycemia and Diabetes Mellitus. Circulation Research 114(4):607-615. PMCID: PMC3954117
  227. Mercado J, Baylie R, Navedo MF, Yuan C, Scott JD, Nelson MT, Brayden JE, and Santana LF (2014) Local control of TRPV4 channels by AKAP150-targeted PKC in arterial smooth muscle. Journal of General Physiology 143:559-575 PMCID: PMC4003184.
  228. Sonkusare SK, Dalsgaard T, Bonev AD, Hill-Eubanks DC, Kotlikoff MI, Scott JD, Santana LF, and Nelson MT (2014) AKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension. Science Signaling 2014 Jul 8;7(333):ra66. PMCID: PMC4403000
  229. Murphy JG, Sanderson JL, Gorski JA, Scott JD, Catterall WA, Sather WA, and Dell’Acqua ML (2014) AKAP-Anchored PKA maintains Neuronal L-type Calcium Channel Activity and NFAT Transcriptional Signaling. Cell Reports 7:1577-1588. PMCID: PMC4136445.
  230. Langeberg LK and Scott JD (2015) Signaling scaffolds and local organization of cellular behaviour. Nature Reviews Molecular Cell Biology 16:232-244. PMCID: PMC4722875
  231. Nieves-Cintron M, Nystoriak MA, Paz Prada M, Johnson K, Fayer W, Dell’Acqua ML, Scott JD, and Navedo MF (2015) Selective Downregulation of KV2.1 Function Contributes to Enhanced Arterial Tone During Diabetes. Journal of Biological Chemistry 290:7918-7929. PMCID: PMC4367290 (Funding erratum: PMCID: PMC4777829)
  232. Kennedy EJ and Scott JD (2015) Selective disruption of the AKAP signaling complexes. In: Zaccolo M, editor. Methods in Molecular Biology New York City, NY: Springer Science & Business Media LLC. 1294: 137-150. PMCID: PMC4722817.
  233. Wang Y, Ho T, Franz E, Hermann J, Smith FD, Hehnly H, Esseltine J, Hanold L, Murph M, Bertinetti D, Scott JD, Herberg F, and Kennedy EJ (2015) PKA-type I Selective Constrained Peptide Disruptors of AKAP Complexes. ACS Chemical Biology 10:1502-1510. PMCID: PMC4475429.
  234. Samelson BK, Gore B, Whiting JL, Nygren P, Purkey AM, Colledge M, Langeberg LK, Dell’Acqua ML, Zweifel LS, and Scott JD (2015) A-kinase Anchoring Protein 79/150 Recruits Protein Kinase C to Phosphorylate Roundabout Receptors. Journal of Biological Chemistry 290:14107-14119. PMCID: PMC4447981.
  235. Whiting JL, Nygren P, Tunquist BJ, Langeberg LK, Seternes O, and Scott JD (2015) Protein Kinase A Opposes the Phosphorylation-Dependent Recruitment of Glycogen Synthase Kinase 3β to A-Kinase Anchoring Protein 220. Journal of Biological Chemistry 290:19445-19457. PMCID: PMC4528109.
  236. Nygren P and Scott JD (2015) Therapeutic strategies for anchored kinases and phosphatases: exploiting short linear motifs and intrinsic disorder. Frontiers in Pharmacology 6:(158):1-10. PMCID: PMC4516873.
  237. Hehnly H, Canton DA, Bucko P, Langeberg LK, Ogier L, Gelman I, Santana LF, Wordeman L, and Scott JD (2015) A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germline stem cells. eLife 2015;4:e09384. PMCID: PMC4612572.
  238. Turnham R and Scott JD (2016) Protein kinase A catalytic subunit isoform PRKACA; history, function and physiology. Gene 577:101-108. PMCID: PMC4713328.
  239. Nieves-Citrón M, Hirenallur-Shanthappa D, Nygren P, Hinke SA, Dell’Acqua ML, Langeberg LK, Navedo MF, Santana LF, and Scott JD (2016) AKAP150 participates in calcineurin/NFAT activation during the down-regulation of voltage-gated K+ currents in ventricular myocytes following myocardial infarction. Cellular Signalling 7:733-740. PMCID: PMC4902329
  240. Riggle KM, Riehle KJ, Kenerson HL, Turnham R, Homma M, Kazami M, Samelson BK, Bauer R, McKnight GS, Scott JD, Yeung RS (2016) Enhanced cAMP-stimulated Protein Kinase A Activity in Human Fibrolamellar Hepatocellular Carcinoma. Pediatric Research 80(1):110-118. PMCID: PMC5105330
  241. Riggle KM, Turnham R, Scott JD, Yeung RS, Riehle KJ (2016), Fibrolamellar Hepatocellular Carcinoma: Mechanistic Distinction From Adult Hepatocellular Carcinoma. Pediatric Blood and Cancer 63:1163-1167. PMCID: PMC4877189.
  242. Cherry AE, Haas BR, Naydenov AV, Fung S, Xu C, Swinney K, Wagenbach M, Freeling J, Canton DA, Coy J, Horne EA, Rickman B, Vicente JJ, Scott JD, Ho RJY, Liggitt D, Wordeman L, Stella N (2016) ST-11: a new brain-penetrant microtubule-destabilizing agent with therapeutic potential for gliomblastoma multiforme. Molecular Cancer Therapeutics 15(9):2018-29. PMCID: PMC5010991.
  243. Scott JD and Newton AC (2016) Bacterial spore coat protein kinases: A new twist to an old story. Proceedings of the National Academy of Sciences USA 113(25):6811-6812. PMCID: PMC4922189
  244. Whiting JL, Ogier L, Forbush K, Bucko P, Gopalan J, Seternes OM, Langeberg LK, and Scott JD (2016) AKAP220 manages apical actin networks that coordinate aquaporin-2 location and renal water reabsorption. Proceedings of the National Academy of Sciences USA 113:E4328-E4337. PMCID: PMC4968721.
  245. Newton AC, Bootman M, and Scott JD (2014) Second Messengers. In: Sever R, editor. Signal Transductions Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press 2014. pp. 51-64.
  246. Bjerregaard-Andersen K, Ostensen E, Scott JD, Tasken K, and Morth JP (2016) Malonate in the nucleotide-binding site traps human AKAP18gamma/delta in a novel conformational state. Acta Crystallographica F Structural Biology Communications. 72(Pt 8):591-597. PMCID: PMC4973299.
  247. Kountz TS, Lee KS, Aggarwal-Howarth S, Curran E, Park JM, Harris DA, Stewart A, Hendrickson J, Camp ND, Wolf-Yadlin A, Wang EH, Scott JD, and Hague C (2016) Endogenous N-terminal Domain Cleavage Modulates alpha1D-Adrenergic Receptor Pharmacodynamics. Journal of Biological Chemistry 291(35):18210-18221. PMCID: PMC5000069.
  248. Nygren P and Scott JD (2016) Regulation of the phosphatase PP2B by protein-protein interactions. Biochemical Society Transactions 44(5):1313-1319. PMCID: PMC5142753
  249. Li L, Li J, Drum BM, Chen Y, Yin H, Guo X, Luckey SW, Gilbert M, McKnight GS, Scott JD, Santana LF, and Liu Q (2017) Loss of AKAP150 promotes pathological remodeling and heart failure propensity by disrupting calcium cycling and contractile reserve. Cardiovascular Research 113:147-159. PMCID: PMC PMC5340143
  250. Nystoriak MA, Nieves-Citrón M, Patriarchi T, Buonarati OR, Prada MP, Morotti S, Grandi E, Fernandes J, Forbush K, Hofmann F, Sasse KC, Scott JD, Ward SM, Hell JW, and Navedo MF (2017) Ser1928 phosphorylation by PKA stimulates the L-type Ca2+ channel Cav2 and vasoconstriction during acute hyperglycemia and diabetes. Science Signaling 10: eaaf9647. PMCID: PMC5297430
  251. Aggarwal-Howarth S and Scott JD (2017) Pseudoscaffolds and anchoring proteins: the difference is in the details. Biochemical Society Transactions 45:371-379. PMCID: PMC5497583
  252. Gabrovsek L, Bucko P, Carnegie GK, and Scott JD (2017) A-Kinase Anchoring Protein (AKAP). In: Choi S, editor. Encyclopedia of Signaling Molecules: Springer New York; 2017. pp1-6.
  253. Smith FD, Esseltine JL, Nygren PJ, Vessler D, Byrne DP, Vonderach M, Strashnov I, Eyers CE, Eyers PA, Langeberg LK, and Scott JD (2017) Local protein kinase A action proceeds through intact holoenzymes. Science 356:1288-1293.
  254. Nygren PJ, Mehta S, Schweppe DK, Langeberg LK, Whiting JL, Weisbrod CR, Bruce JE, Zhang J, Veesler D, and Scott JD (2017) Intrinsic disorder within AKAP79 fine-tunes anchored phosphatase activity toward substrates and drug sensitivity. eLife epub AOP Oct 2, 2017. PMCID: PMC5653234
  255. Sanderson JL, Scott JD, and Dell’Acqua ML (2018) Control of Homeostatic Synaptic Plasticity by AKAP-Anchored Kinase and phosphatase Regulation of Ca2+-Permeable AMPA Receptors. Journal of Neuroscience. Journal of Neuroscience 38:2863-2876.
  256. Smith FD and Scott JD (2018) Protein Kinase A activation: something new under the sun? J Cell Biol 217(6):1895-1897. PMID: 29773583 PMCID: PMC5987730
  257. Smith FD, Nygren P, Soughayer J, Hoshi N, Snyder CG, Langeberg LK, and Scott JD (2018) Single nucleiotide polymorphisms alter kinase anchoring and the subcellular targeting of A-Kinase Anchoring Proteins. Proc Natl Acad Sci U S A 115(49):E11465-E11474. PMID: 30455320 PMCID: PMC6298107
  258. Aggarwal-Howarth S, Gabrovsek L, Langeberg LK, Golkowski M, Ong S, Smith FD, and Scott JD (2018) Depletion of dAKAP-1-signaling islands during breast cancer metastasis accompanies pathological changes in mitochrondrial dynamics. J Biol Chem 294(9):3152-3168. PMID: 30598507 PMCID: PMC6398132
  259. Kastenhuber ER, Craig J, Ramsey J, Sullivan KM, Sage J, de Oliveira S, Riehle KJ, Scott JD, Gordan JD, Bardeesy N, Abou-Alfa GK (2019) Road map for fibrolamellar carcinoma: progress and goals of a diversified approach. J Hepatocell Carcinoma 6:41-48. eCollection 2019. PMID: 30951568 PMCID: PMC6362920
  260. Dinh TA, Jewell ML, Kanke M, Francisco A, Sritharan R, Turnham RE, Lee S, Kastenhuber ER, Wauthier E, Guy CD, Yeung RS, Lowe SW, Reid LM, Scott JD, Diehl AM, Sethupathy P. (2019) MicroRNA-375 suppresses the growth and invasion of fibrolamellar carcinoma. Cell Mol Gastroenterol Hepatol. 2019;7(4):803-817. PMID: 30763770 PMCID: PMC6468197
  261. Turnham RE, Smith FD, Kenerson HL, Omar MH, Golkowski M, Garcia I, Bauer R, Lau HT, Sullivan KM, Langeberg LK, Ong SE, Riehle KJ, Yeung RS, Scott JD. (2019) An acquired scaffolding function of the DNAJ-PKAc fusion contributes to oncogenic signaling in fibrolamellar carcinoma. Elife. pii: e44187. PMID: 31063128 PMCID: PMC6533061
  262. Riehle KJ, Kenerson HL, Riggle KM, Turnham R, Sullivan K, Bauer R, Scott JD, Yeung RS. (2019) Neurotensin as a source of cyclic AMP and co-mitogen in fibrolamellar hepatocellular carcinoma. 10(49):5092-5102. PMID: 31489118 PMCID: PMC6707953
  263. Verma NK, Chalasani MLS, Scott JD, Kelleher D. (2019) CG-NAP/Kinase Interactions Fine-Tune T Cell Functions. Front Immunol. 10:2642. Review. PMID: 31781123 PMCID: PMC6861388
  264. Bucko PJ, Lombard CK, Rathbun L, Garcia I, Bhat A, Wordeman L, Smith FD, Maly DJ, Hehnly H, Scott JD. Subcellular drug targeting illuminates local kinase action. (2019) Elife. 2019 Dec 24;8. pii: e52220. PMID: 31872801 PMCID: PMC6930117
  265. Dinh TA, Sritharan R, Smith FD, Francisco AB, Ma RK, Bunaciu RP, Kanke M, Danko CG, Massa AP, Scott JD, Sethupathy P. (2020) Hotspots of Aberrant Enhancer Activity in Fibrolamellar Carcinoma Reveal Candidate Oncogenic Pathways and Therapeutic Vulnerabilities. Cell Rep. 31(2):107509. PMID: 32294439
  266. Bucko PJ, Scott JD. (2020) Drugs that Regulate Local Cell Signaling: AKAP Targeting as a Therapeutic Option. Annu Rev Pharmacol Toxicol. 61:361-379. PMID: 32628872
  267. Bucko PJ, Garcia I, Manocha R, Bhat A, Wordeman L, Scott JD. (2020) Gravin-associated kinase signaling networks coordinate γ-tubulin organization at mitotic spindle poles. J Biol Chem 295(40):13784-13797. PMID: 32732289
  268. Gabrovsek L, Collins KB, Aggarwal S, Saunders LM, Lau HT, Suh D, Sancak Y, Trapnell C, Ong SE, Smith FD, Scott JD. (2020) A-kinase-anchoring protein 1 (dAKAP1)-based signaling complexes coordinate local protein synthesis at the mitochondrial surface. J Biol Chem 295(31):10749-10765. PMID: 32482893 PMCID: PMC7397098
  269. Omar MH, Scott JD. (2020) AKAP Signaling Islands: Venues for Precision Pharmacology. Trends Pharmacol Sci 17:S0165-6147(20)30213-3. PMID: 33082006
  270. Prada MP, Syed AU, Reddy GR, Martín-Aragón Baudel M, Flores-Tamez VA, Sasse KC, Ward SM, Sirish P, Chiamvimonvat N, Bartels P, Dickson EJ, Hell JW, Scott JD, Santana LF, Xiang YK, Navedo MF, Nieves-Cintrón M. (2020) AKAP5 complex facilitates purinergic modulation of vascular L-type Ca2+ channel CaV2. Nat Commun 11(1):5303. PMID: 33082339
  271. Gopalan J, Wordeman L, Scott JD. (2021) Kinase-anchoring proteins in ciliary signal transduction. Biochem J 478(8):1617-1629. PMID: 33909027
  272. Watson L, Soliman TN, Davis K, Kelly J, Lockwood N, Yang X, Lynham S, Scott JD, Crossland V, McDonald NQ, Mann DJ, Armstrong A, Eggert U, Parker PJ. (2021) Co-ordinated control of the Aurora B abscission checkpoint by PKCε complex assembly, midbody recruitment and retention. Biochem J 478(12):2247-2263. PMID: 34143863
  273. Dahlin HR, Zheng N, Scott JD. (2021) Beyond PKA: Evolutionary and Structural Insights that Define a Docking and Dimerization Domain Superfamily. J Biol Chem 297(2):100927
  274. Gopalan J, Omar MH, Roy A, Cruz NM, Falcone J, Jones KN, Forbush KA, Himmelfarb J, Freedman BS, Scott JD. (2021) Targeting an anchored phosphatase-deacetylase unit restores renal ciliary homeostasis. Elife. 10:e67828. PMID: 34250905
  275. Scott JD, Davis TN, Klevit RE, Catterall WA. (2021) Edmond Fischer (1920-2021) Science. 374(6564):157.
  276. Dinh TA, Utria AF, Barry KC, Ma R, Abou-Alfa GK, Gordan JD, Jaffee EM, Scott JD, Zucman-Rossi J, O’Neill AF, Furth ME, Sethupathy P. (2022) A framework for fibrolamellar carcinoma research and clinical trials. Nat Rev Gastroenterol Hepatol. 19(5):328-342. PMID: 35190728 PMCID: PMC9516439
  277. Byrne DP, Omar MH, Kennedy EJ, Eyers PA, Scott JD. (2022) Biochemical Analysis of AKAP-Anchored PKA Signaling Complexes. Manuela Zaccolo (ed.) cAMP Signaling: Methods and Protocols, Methods in Molecular Biology, second edition, vol. 2483 Springer Nature 2022
  278. Omar MH, Byrne DP, Jones KN, Lakey TM, Collins KB, Lee KS, Daly LA, Forbush KA, Lau HT, Golkowski M, McKnight GS, Breault DT, Lefrançois-Martinez AM, Martinez A, Eyers CE, Baird GS, Ong SE, Smith FD, Eyers PA, Scott JD. 2022 Mislocalization of protein kinase A drives pathology in Cushing’s syndrome. Cell Rep. 2022 Jul 12;40(2):111073. PMID: 35830806
  279. Collins KB, Scott JD. (2022) Phosphorylation, compartmentalization, and cardiac function. IUBMB Life. 75(4):353-369. PMCID: PMC10049969
  280. Chan GKL, Maisel S, Hwang YC, Pascual BC, Wolber RRB, Vu P, Patra KC, Bouhaddou M, Kenerson HL, Lim HC, Long D, Yeung RS, Swaney DL, Krogan NJ, Sethupathy P, Turnham RE, Riehle KJ, Scott JD, Bardeesy N, Gordan JD. (2023) Oncogenic PKA increases MYC protein expression through targetable signaling mechanisms. elife. 12:e69521. PMCID: PMC9925115
  281. Omar MH, Kihiu M, Byrne DP, Lee KS, Lakey TM, Butcher E, Eyers PA, Scott JD. (2023) Classification of Cushing’s syndrome PKAc mutants based upon their ability to bind PKI. Biochem J. 2023 Jun 28;480(12):875-890. PMID: 37306403
  282. Omar MH, Lauer SM, Lau H-T, Golkowski M, Ong SE, Scott JD (2023) Proximity biotinylation to define the local environment of PKA catalytic subunit in adrenal cells. Star Protocol. 4(1):101992. PMCID: PMC9826815
  283. Lauer SM, Omar MH, Golkowski MG, Kenerson HL, Pascual BC, Forbush K, Smith FD, Gordan J, Ong SE, Yeung RS, Scott JD. (2023) Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma. Cell Rep. 2024 Feb 27;43(2):113678. PMID: 38236773
  284. Omar MH, Byrne DP, Shrestha S, Lakey TM, Lee KS, Lauer SM, Collins KB, Daly LA, Eyers CE, Baird GS, Ong SE, Kannan N, Eyers PA, Scott JD. (2024) Discovery of a Cushing’s syndrome protein kinase A mutant that biases signaling through type I AKAPs. Sci Adv. 2024 Feb 23;10(8):eadl1258. PMID: 38381834 PMCID: PMC10881042
  285. Bock A, Irannejad R, Scott JD. cAMP signaling: a remarkably regional affair. (2024) Trends Biochem Sci. 2024 Feb 2:S0968-0004(24)00018-5. PMID: 38310024